SPHIRO™ MT
Mannitol Pellets
Sugar-Free Starter Pellets for Pharmaceutical & Nutraceutical Applications
SPHIRO™ MT are pharmaceutical-grade spherical starter pellets manufactured from mannitol.
They are designed as sugar-free starter cores for active-ingredient layering and functional coating in pharmaceutical and nutraceutical oral solid dosage forms.
Mannitol provides an alternative core platform for formulation developers who prefer a mannitol-based, sugar-free starter pellet rather than a conventional sucrose-based core.
SPHIRO™ MT are manufactured with controlled particle size distribution and spherical geometry to support consistent layering, coating and downstream processing.

Pharmaceutical Applications
- API Drug Layering
- Immediate-Release Pellets
- Modified-Release Pellets
- Functional Coating
- Multiparticulate Dosage Forms
- MUPS Tablets
- Hard Gelatin Capsules
Nutraceutical Applications
- Vitamin & Mineral Layering
- Botanical Active Loading
- Herbal Extract Layering
- Nutraceutical Active Coating
- Sugar-Free Nutraceutical Formulations
- Multiparticulate Nutraceutical Systems
- Capsules
- Tablets
- Sachets
Low Microbiological Contamination
Manufactured under controlled production conditions using appropriate pharmaceutical-grade raw materials, with microbiological quality routinely monitored and evaluated against established product specifications as part of MEB Pharma's quality-control programme.
Pharmacopeial Compliance
- USP–NF
- BP
- Ph. Eur.
- IP
Product Characteristics
- Pharmaceutical-grade mannitol
- Mannitol-based starter pellet
- Sugar-free core platform
- Spherical particle geometry
- Controlled particle size distribution
- Suitable for active-ingredient layering
- Suitable for functional coating
- Compatible with fluid-bed processing
- Multiple particle size grades
Why SPHIRO™ MT?
A sugar-free mannitol-based starter platform for pharmaceutical and nutraceutical manufacturers seeking an alternative to conventional sucrose-based starter cores.
